We found that CD106 (VCAM-1) was expressed highest on the CV-MSCs, moderately on BM-MSCs, lightly on UC-MSCs and absent on AD-MSCs. CV-MSCs also showed unique immune-associated gene expression and immunomodulation. We thus separated CD106 (+)cells and CD106 (-)cells from CV-MSCs and compared their biological activities.
Description: The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation.
CD106 is a 100-110 kDa type I transmembrane sialoglycoprotrein that is also known as Vascular cell adhesion molecule-1 (VCAM-1) and INCAM-110. CD106 is expressed at high levels on the surface of cytokine-stimulated endothelium, and at minimal levels on unstimulated endothelium. VCAM-1 serves as a ligand for the leukocyte integrins α4β1
VCAM-1 (CD106), a member of the immunoglobulin superfamily, is a cell surface protein expressed by activated endothelial cells and certain leukocytes (such as macrophages). VCAM-1 expression is induced by IL-1 beta, IL-4, TNF-alpha and IFN-gamma. VCAM-1 binds to leukocyte integrins VLA-4 and alpha 4 beta 7. The human and mouse VCAM-1
Western blot was performed using Anti-VCAM-1 (CD106) Recombinant Rabbit Monoclonal Antibody (SA05-04) (Product # MA5-31965) and an 80 kDa band corresponding to Vascular cell adhesion protein 1 was induced in HUVEC cells on treatment and also in tissues tested. An additional band around 35 kDa corresponding to the lower isoform was observed on
The MR106 antibody reacts with CD106, the ~110 kDa transmembrane vascular cell adhesion molecule-1 (VCAM-1). Expression of CD106 on endothelial cells is induced by inflammatory cytokines and in certain pathologic conditions. In the rat bone marrow, CD106 has been reported to be expressed on dendritic cells and subsets of the myeloid lineage
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BD Pharmingen Technical Data Sheet PE Mouse Anti-Human CD106 Product Information Material Number: 555647 Alternate Name: VCAM-1; Vascular cell adhesion protein 1; INCAM-100; L1CAMSize: 100 Tests Vol. per Test: 20 µl Clone: 51-10C9Immunogen: Human VCAM-1 Recombinant Protein
Used products : 130-122-339. Clone REA269 recognizes the CD106 antigen, a 110 kDa single chain type I glycoprotein, also known as vascular cell adhesion protein 1 (VCAM-1) or INCAM-100. CD106 is expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.
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. Abcam’s Human VCAM1 (CD106) in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative measurement of VCAM1 in cell culture supernatants, buffered solutions, serum, plasma, and other body fluids. A monoclonal antibody specific for VCAM1 has been coated onto the wells of the microtiter strips
Suggested Companion Products Catalog Number Name Size Clone 559073 Purified Rat IgG2a κ Isotype Control 0.25 mg R35-95 559286 Biotin Goat Anti-Rat Ig 0.5 mg Polyclonal 550946 Streptavidin HRP 50 ml (none) 550880 DAB Substrate Kit 500 tests (none)
VCAM-1 (CD106), a member of the immunoglobulin superfamily, is a cell surface protein expressed by activated endothelial cells and certain leukocytes (such as macrophages). VCAM-1 expression is induced by IL-1 beta, IL-4, TNF-alpha, and IFN-gamma. VCAM-1 binds to leukocyte integrins VLA-4 and alpha 4 beta 7. The human and mouse VCAM-1
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The BD™ CBA Human sCD106 (VCAM-1) Flex Set is a bead-based immunoassay capable of measuring soluble human soluble CD106 also known as VCAM-1, in serum, plasma and cell culture supernatant samples. Human reactivity was determined by testing samples with the BD CBA sCD106 (VCAM-1) Flex Set. The biology and function of sCD106 (VCAM-1)
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Product Specific Information. Description: The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation.
Product Specific Information. Description: The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation.
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